Detection and clinical significance of minimal tumor cell contamination of peripheral stem call harvests

J. G. Sharp; A. Kessinger; W. P. Vaughan; S. Mann; D. A. Crouse; K. Dicke; A. Masih; D. D. Weisenburger

doi:10.1002/stem.5530100731

Detection and clinical significance of minimal tumor cell contamination of peripheral stem call harvests

J. G. Sharp, A. Kessinger, W. P. Vaughan, S. Mann, D. A. Crouse, K. Dicke, A. Masih, D. D. Weisenburger

Research output: Contribution to journal › Article › peer-review

115 Scopus citations

Abstract

Peripheral stem cell (PSC) harvests from patients with non‐Hodgkin's lymphoma (NHL) and breast cancer are less likely to be contaminated with occult tumor cells detected by culture techniques, than are bone marrow harvests. Clinically, NHL patients transplanted with such PSC harvests had a better outcome than recipients of bone marrow harvests.

Original language	English (US)
Pages (from-to)	92-94
Number of pages	3
Journal	The International Journal of Cell Cloning
Volume	10
Issue number	1 S
DOIs	https://doi.org/10.1002/stem.5530100731
State	Published - Jan 1992

Keywords

Peripheral
Tumor cell cultures
cell transplantation
stem

ASJC Scopus subject areas

Cell Biology

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10.1002/stem.5530100731

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abstract = "Peripheral stem cell (PSC) harvests from patients with non‐Hodgkin's lymphoma (NHL) and breast cancer are less likely to be contaminated with occult tumor cells detected by culture techniques, than are bone marrow harvests. Clinically, NHL patients transplanted with such PSC harvests had a better outcome than recipients of bone marrow harvests.",

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AU - Sharp, J. G.

AU - Kessinger, A.

AU - Vaughan, W. P.

AU - Mann, S.

AU - Crouse, D. A.

AU - Dicke, K.

AU - Masih, A.

AU - Weisenburger, D. D.

PY - 1992/1

Y1 - 1992/1

N2 - Peripheral stem cell (PSC) harvests from patients with non‐Hodgkin's lymphoma (NHL) and breast cancer are less likely to be contaminated with occult tumor cells detected by culture techniques, than are bone marrow harvests. Clinically, NHL patients transplanted with such PSC harvests had a better outcome than recipients of bone marrow harvests.

AB - Peripheral stem cell (PSC) harvests from patients with non‐Hodgkin's lymphoma (NHL) and breast cancer are less likely to be contaminated with occult tumor cells detected by culture techniques, than are bone marrow harvests. Clinically, NHL patients transplanted with such PSC harvests had a better outcome than recipients of bone marrow harvests.

KW - Peripheral

KW - Tumor cell cultures

KW - cell transplantation

KW - stem

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Detection and clinical significance of minimal tumor cell contamination of peripheral stem call harvests

Abstract

Keywords

ASJC Scopus subject areas

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