Abstract
Analysis of urine specimens by using reverse transcriptase-PCR was evaluated as a rapid assay to identify individuals infected with measles virus. For the study, daily urine samples were obtained from either 15- month-old children or young adults following measles immunization. Overall, measles virus RNA was detected in 10 of 12 children during the 2-week sampling period. In some cases, measles virus RNA was detected as early as 1 day or as late as 14 days after vaccination. Measles virus RNA was also detected in the urine samples from all four of the young adults between 1 and 13 days after vaccination. This assay will enable continued studies of the shedding and transmission of measles virus and, it is hoped, will provide a rapid means to identify measles infection, especially in mild or asymptomatic cases.
Original language | English (US) |
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Pages (from-to) | 2485-2488 |
Number of pages | 4 |
Journal | Journal of clinical microbiology |
Volume | 33 |
Issue number | 9 |
DOIs |
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State | Published - 1995 |
Externally published | Yes |
ASJC Scopus subject areas
- Microbiology (medical)