Diabetic glomerulopathy: Unusual patterns and dual disease

Kirk Foster, Luis Salinas-Madrigal, Brent Miller, Helen Liapis

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

Diabetic glomerulopathy is a well-recognized consequence of both type I and type II diabetes. Occasionally, pathologic diagnosis may be challenging for the pathologist. These circumstances include atypical light microscopy or diabetic change with a second superimposed glomerulopathy (dual disease). We have compiled a selection of 12 renal biopsies from diabetic patients that show either an unusual pattern of nephropathy or "dual disease," as well as 2 cases in which the patient had no history of diabetes but had renal biopsies exhibiting changes consistent with diabetic nephropathy. The salient diagnostic features are discussed. To accurately assess these biopsies, immunofluorescence and electron microscopy become essential, and a broadened differential diagnosis must be considered.

Original languageEnglish (US)
Pages (from-to)160-174
Number of pages15
JournalSeminars in Diagnostic Pathology
Volume19
Issue number3
StatePublished - 2002

Keywords

  • Diabetic glomerulopathy
  • Disease
  • Dual
  • Unusual

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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