Diagnostic utility of the international hiv dementia scale for hiv associated neurocognitive impairment and disorder in South Africa

Karl Goodkin, David J. Hardy, Dinesh Singh, Enrique Lopez

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Studies in sub-Saharan Africa indicate that most HIV seropositive persons have HIV-associated neurocognitive disorder (HAND). HAND diagnosis is facilitated by specific screening. Seventy participants were recruited from an HIV voluntary counseling and testing clinic in Durban, South Africa. The diagnostic utility of the International HIV Dementia Scale (IHDS) was analyzed using a receiver operating characteristic (ROC) model. The ROC analysis comparing any HAND diagnosis (based on two neuropsychological tests) versus no diagnosis was statistically significant, with an optimal cut-off score of 10.5, sensitivity of 69%, and specificity of 74%. Sensitivity of the IHDS was highest for HIVassociated dementia.

Original languageEnglish (US)
Pages (from-to)352-358
Number of pages7
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume26
Issue number4
DOIs
StatePublished - Jan 1 2014

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ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

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