Diagnostics for SARS-CoV-2 infections

Bhavesh D. Kevadiya; Jatin Machhi; Jonathan Herskovitz; Maxim D. Oleynikov; Wilson R. Blomberg; Neha Bajwa; Dhruvkumar Soni; Srijanee Das; Mahmudul Hasan; Milankumar Patel; Ahmed M. Senan; Santhi Gorantla; Jo Ellyn McMillan; Benson Edagwa; Robert Eisenberg; Channabasavaiah B. Gurumurthy; St Patrick M. Reid; Chamindie Punyadeera; Linda Chang; Howard E. Gendelman

doi:10.1038/s41563-020-00906-z

Diagnostics for SARS-CoV-2 infections

Bhavesh D. Kevadiya, Jatin Machhi, Jonathan Herskovitz, Maxim D. Oleynikov, Wilson R. Blomberg, Neha Bajwa, Dhruvkumar Soni, Srijanee Das, Mahmudul Hasan, Milankumar Patel, Ahmed M. Senan, Santhi Gorantla, Jo Ellyn McMillan, Benson Edagwa, Robert Eisenberg, Channabasavaiah B. Gurumurthy, St Patrick M. Reid, Chamindie Punyadeera, Linda Chang, Howard E. Gendelman

Research output: Contribution to journal › Review article › peer-review

14 Scopus citations

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every corner of the globe, causing societal instability. The resultant coronavirus disease 2019 (COVID-19) leads to fever, sore throat, cough, chest and muscle pain, dyspnoea, confusion, anosmia, ageusia and headache. These can progress to life-threatening respiratory insufficiency, also affecting the heart, kidney, liver and nervous systems. The diagnosis of SARS-CoV-2 infection is often confused with that of influenza and seasonal upper respiratory tract viral infections. Due to available treatment strategies and required containments, rapid diagnosis is mandated. This Review brings clarity to the rapidly growing body of available and in-development diagnostic tests, including nanomaterial-based tools. It serves as a resource guide for scientists, physicians, students and the public at large.

Original language	English (US)
Pages (from-to)	593-605
Number of pages	13
Journal	Nature Materials
Volume	20
Issue number	5
DOIs	https://doi.org/10.1038/s41563-020-00906-z
State	Published - May 2021

ASJC Scopus subject areas

Chemistry(all)
Materials Science(all)
Condensed Matter Physics
Mechanics of Materials
Mechanical Engineering

Access to Document

10.1038/s41563-020-00906-z

Cite this

Kevadiya, B. D., Machhi, J., Herskovitz, J., Oleynikov, M. D., Blomberg, W. R., Bajwa, N., Soni, D., Das, S., Hasan, M., Patel, M., Senan, A. M., Gorantla, S., McMillan, J. E., Edagwa, B., Eisenberg, R., Gurumurthy, C. B., Reid, S. P. M., Punyadeera, C., Chang, L., & Gendelman, H. E. (2021). Diagnostics for SARS-CoV-2 infections. Nature Materials, 20(5), 593-605. https://doi.org/10.1038/s41563-020-00906-z

Diagnostics for SARS-CoV-2 infections. / Kevadiya, Bhavesh D.; Machhi, Jatin; Herskovitz, Jonathan; Oleynikov, Maxim D.; Blomberg, Wilson R.; Bajwa, Neha; Soni, Dhruvkumar; Das, Srijanee; Hasan, Mahmudul; Patel, Milankumar; Senan, Ahmed M.; Gorantla, Santhi ; McMillan, Jo Ellyn ; Edagwa, Benson; Eisenberg, Robert; Gurumurthy, Channabasavaiah B.; Reid, St Patrick M.; Punyadeera, Chamindie; Chang, Linda; Gendelman, Howard E.

In: Nature Materials, Vol. 20, No. 5, 05.2021, p. 593-605.

Research output: Contribution to journal › Review article › peer-review

Kevadiya, BD, Machhi, J, Herskovitz, J, Oleynikov, MD, Blomberg, WR, Bajwa, N, Soni, D, Das, S, Hasan, M, Patel, M, Senan, AM, Gorantla, S , McMillan, JE , Edagwa, B, Eisenberg, R, Gurumurthy, CB , Reid, SPM, Punyadeera, C, Chang, L & Gendelman, HE 2021, 'Diagnostics for SARS-CoV-2 infections', Nature Materials, vol. 20, no. 5, pp. 593-605. https://doi.org/10.1038/s41563-020-00906-z

Kevadiya, Bhavesh D. ; Machhi, Jatin ; Herskovitz, Jonathan ; Oleynikov, Maxim D. ; Blomberg, Wilson R. ; Bajwa, Neha ; Soni, Dhruvkumar ; Das, Srijanee ; Hasan, Mahmudul ; Patel, Milankumar ; Senan, Ahmed M. ; Gorantla, Santhi ; McMillan, Jo Ellyn ; Edagwa, Benson ; Eisenberg, Robert ; Gurumurthy, Channabasavaiah B. ; Reid, St Patrick M. ; Punyadeera, Chamindie ; Chang, Linda ; Gendelman, Howard E. / Diagnostics for SARS-CoV-2 infections. In: Nature Materials. 2021 ; Vol. 20, No. 5. pp. 593-605.

@article{a4ec48e07f6641d2b770dc098c67bad7,

title = "Diagnostics for SARS-CoV-2 infections",

abstract = "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every corner of the globe, causing societal instability. The resultant coronavirus disease 2019 (COVID-19) leads to fever, sore throat, cough, chest and muscle pain, dyspnoea, confusion, anosmia, ageusia and headache. These can progress to life-threatening respiratory insufficiency, also affecting the heart, kidney, liver and nervous systems. The diagnosis of SARS-CoV-2 infection is often confused with that of influenza and seasonal upper respiratory tract viral infections. Due to available treatment strategies and required containments, rapid diagnosis is mandated. This Review brings clarity to the rapidly growing body of available and in-development diagnostic tests, including nanomaterial-based tools. It serves as a resource guide for scientists, physicians, students and the public at large.",

author = "Kevadiya, {Bhavesh D.} and Jatin Machhi and Jonathan Herskovitz and Oleynikov, {Maxim D.} and Blomberg, {Wilson R.} and Neha Bajwa and Dhruvkumar Soni and Srijanee Das and Mahmudul Hasan and Milankumar Patel and Senan, {Ahmed M.} and Santhi Gorantla and McMillan, {Jo Ellyn} and Benson Edagwa and Robert Eisenberg and Gurumurthy, {Channabasavaiah B.} and Reid, {St Patrick M.} and Chamindie Punyadeera and Linda Chang and Gendelman, {Howard E.}",

note = "Funding Information: We thank D. Meigs, University of Nebraska Medical Center, for proofreading and providing feedback on the manuscript. This work was supported by the National Institutes of Health R01 MH121402-01A1, R01 MH121402P01, R01 AG043540, R01 AG043530, P01 DA028555, P30 MH062261, R01 MH115860, R01 NS034249, R01 NS036126, the Carol Swartz Emerging Neuroscience Fund and the Margaret R. Larson Professorship. C.P. receives support from Cancer Australia (APP1145657) and the Garnett Pass{\'e} and Rodney Williams Foundation. Publisher Copyright: {\textcopyright} 2021, Springer Nature Limited.",

year = "2021",

month = may,

doi = "10.1038/s41563-020-00906-z",

language = "English (US)",

volume = "20",

pages = "593--605",

journal = "Nature Materials",

issn = "1476-1122",

publisher = "Nature Publishing Group",

number = "5",

}

TY - JOUR

T1 - Diagnostics for SARS-CoV-2 infections

AU - Kevadiya, Bhavesh D.

AU - Machhi, Jatin

AU - Herskovitz, Jonathan

AU - Oleynikov, Maxim D.

AU - Blomberg, Wilson R.

AU - Bajwa, Neha

AU - Soni, Dhruvkumar

AU - Das, Srijanee

AU - Hasan, Mahmudul

AU - Patel, Milankumar

AU - Senan, Ahmed M.

AU - Gorantla, Santhi

AU - McMillan, Jo Ellyn

AU - Edagwa, Benson

AU - Eisenberg, Robert

AU - Gurumurthy, Channabasavaiah B.

AU - Reid, St Patrick M.

AU - Punyadeera, Chamindie

AU - Chang, Linda

AU - Gendelman, Howard E.

N1 - Funding Information: We thank D. Meigs, University of Nebraska Medical Center, for proofreading and providing feedback on the manuscript. This work was supported by the National Institutes of Health R01 MH121402-01A1, R01 MH121402P01, R01 AG043540, R01 AG043530, P01 DA028555, P30 MH062261, R01 MH115860, R01 NS034249, R01 NS036126, the Carol Swartz Emerging Neuroscience Fund and the Margaret R. Larson Professorship. C.P. receives support from Cancer Australia (APP1145657) and the Garnett Passé and Rodney Williams Foundation. Publisher Copyright: © 2021, Springer Nature Limited.

PY - 2021/5

Y1 - 2021/5

N2 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every corner of the globe, causing societal instability. The resultant coronavirus disease 2019 (COVID-19) leads to fever, sore throat, cough, chest and muscle pain, dyspnoea, confusion, anosmia, ageusia and headache. These can progress to life-threatening respiratory insufficiency, also affecting the heart, kidney, liver and nervous systems. The diagnosis of SARS-CoV-2 infection is often confused with that of influenza and seasonal upper respiratory tract viral infections. Due to available treatment strategies and required containments, rapid diagnosis is mandated. This Review brings clarity to the rapidly growing body of available and in-development diagnostic tests, including nanomaterial-based tools. It serves as a resource guide for scientists, physicians, students and the public at large.

AB - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every corner of the globe, causing societal instability. The resultant coronavirus disease 2019 (COVID-19) leads to fever, sore throat, cough, chest and muscle pain, dyspnoea, confusion, anosmia, ageusia and headache. These can progress to life-threatening respiratory insufficiency, also affecting the heart, kidney, liver and nervous systems. The diagnosis of SARS-CoV-2 infection is often confused with that of influenza and seasonal upper respiratory tract viral infections. Due to available treatment strategies and required containments, rapid diagnosis is mandated. This Review brings clarity to the rapidly growing body of available and in-development diagnostic tests, including nanomaterial-based tools. It serves as a resource guide for scientists, physicians, students and the public at large.

UR - http://www.scopus.com/inward/record.url?scp=85101463016&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85101463016&partnerID=8YFLogxK

U2 - 10.1038/s41563-020-00906-z

DO - 10.1038/s41563-020-00906-z

M3 - Review article

C2 - 33589798

AN - SCOPUS:85101463016

VL - 20

SP - 593

EP - 605

JO - Nature Materials

JF - Nature Materials

SN - 1476-1122

IS - 5

ER -

Diagnostics for SARS-CoV-2 infections

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this