Differential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons

Suzanne Tydlacka, Chuan En Wang, Xuejun Wang, Shihua Li, Xiao Jiang Li

Research output: Contribution to journalArticlepeer-review

114 Scopus citations

Abstract

Original languageEnglish (US)
Pages (from-to)13285-13295
Number of pages11
JournalJournal of Neuroscience
Volume28
Issue number49
DOIs
StatePublished - Dec 3 2008
Externally publishedYes

Keywords

  • Aggregates
  • Degeneration
  • Huntingtin
  • Polyglutamine
  • Proteasome
  • Ubiquitin

ASJC Scopus subject areas

  • Neuroscience(all)

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