Differential effects of chronic nicotine administration on dopaminergic receptor binding sites in rat nigrostriatal and mesolimbic regions

Yiu K. Fung; Yuen Sum Lau

doi:10.1016/0306-3623(91)90320-6

Differential effects of chronic nicotine administration on dopaminergic receptor binding sites in rat nigrostriatal and mesolimbic regions

Yiu K. Fung, Yuen Sum Lau

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Abstract

1. 1. The effects of chronic (14 day) administration of nicotine (1.5 mg/kg/day) on the striatal and mesolimbic dopaminergic receptor binding sites were determined. 2. 2. Chronic administration of nicotine preferentially increased the number of dopaminergic receptor binding sites in the striatal, but not the mesolimbic area of rat brain.

Original language	English (US)
Pages (from-to)	117-119
Number of pages	3
Journal	General Pharmacology
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/0306-3623(91)90320-6
State	Published - 1991

ASJC Scopus subject areas

Pharmacology

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10.1016/0306-3623(91)90320-6

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title = "Differential effects of chronic nicotine administration on dopaminergic receptor binding sites in rat nigrostriatal and mesolimbic regions",

abstract = "1. 1. The effects of chronic (14 day) administration of nicotine (1.5 mg/kg/day) on the striatal and mesolimbic dopaminergic receptor binding sites were determined. 2. 2. Chronic administration of nicotine preferentially increased the number of dopaminergic receptor binding sites in the striatal, but not the mesolimbic area of rat brain.",

author = "Fung, {Yiu K.} and Lau, {Yuen Sum}",

note = "Funding Information: Acknowledgements--This work was supported by a grant from the Smokeless Tobacco Research Council, Inc., New York. We wish to thank Karen Trobough and Lori Fiske for their technical assistance.",

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T1 - Differential effects of chronic nicotine administration on dopaminergic receptor binding sites in rat nigrostriatal and mesolimbic regions

AU - Fung, Yiu K.

AU - Lau, Yuen Sum

N1 - Funding Information: Acknowledgements--This work was supported by a grant from the Smokeless Tobacco Research Council, Inc., New York. We wish to thank Karen Trobough and Lori Fiske for their technical assistance.

PY - 1991

Y1 - 1991

N2 - 1. 1. The effects of chronic (14 day) administration of nicotine (1.5 mg/kg/day) on the striatal and mesolimbic dopaminergic receptor binding sites were determined. 2. 2. Chronic administration of nicotine preferentially increased the number of dopaminergic receptor binding sites in the striatal, but not the mesolimbic area of rat brain.

AB - 1. 1. The effects of chronic (14 day) administration of nicotine (1.5 mg/kg/day) on the striatal and mesolimbic dopaminergic receptor binding sites were determined. 2. 2. Chronic administration of nicotine preferentially increased the number of dopaminergic receptor binding sites in the striatal, but not the mesolimbic area of rat brain.

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JO - General Pharmacology

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ER -

Differential effects of chronic nicotine administration on dopaminergic receptor binding sites in rat nigrostriatal and mesolimbic regions

Abstract

ASJC Scopus subject areas

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