Dimers of isatin derived α-methylene-γ-butyrolactone as potent anti-cancer agents

Keyphrases

• Methylene 100%
• Anticancer Agents 100%
• γ-butyrolactone 100%
• Isatin 100%
• Covalent Modifier 100%
• Cancer Cells 33%
• Induced Apoptosis 33%
• Gene Expression 33%
• Transcription Factor 33%
• Phosphorylation 33%
• Cell-based 33%
• Hematological Malignancies 33%
• Cysteine Residues 33%
• Extracellular Signaling 33%
• Leukemia Cell Lines 33%
• Nuclear Translocation 33%
• Colony Formation 33%
• High-molecular-weight Complexes 33%
• Cell-free 33%
• Michael Acceptor 33%
• Signaling Nodes 33%
• Spirocyclic 33%
• NCI-60 Cell Lines 33%
• Therapeutic Leads 33%
• Colony Relocation 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Anticarcinogen 100%
• Dimer 100%
• Carbene 100%
• Isatin 100%
• Butyrolactone 100%
• Malignant Neoplasm 33%
• Phosphotransferase 33%
• Cysteine 33%
• Tumor Necrosis Factor 33%
• Transcription Factors 33%
• Hematologic Malignancy 33%
• Leukemia 33%