Abstract
N-Fmoc-3-O-Tr-l-serine methyl and benzyl esters, as well as a tripeptide FmocAlaSer(Tr)GlyOBn were directly glycosylated by 3,4,6-tri-O-acetyl-1,2-O-(1-cyanoethylidene)-α-d-galactopyranose in the presence of TrClO4 in dichloromethane, yielding 32-57% of N-Fmoc-3-O-(2,3,4,6-tetra-O-acetyl-β-d-galactopyranosyl)-l-serine esters and the corresponding tripeptide.
Original language | English (US) |
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Pages (from-to) | 123-136 |
Number of pages | 14 |
Journal | Carbohydrate Research |
Volume | 274 |
Issue number | C |
DOIs | |
State | Published - Sep 8 1995 |
Externally published | Yes |
Keywords
- Cyanoethylidene condensation
- Glycosylation
- N-9-Fluorenylmethoxycarbonyl-O-tritylserine esters
- Serine glycopeptides
- Serine glycosides
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
- Organic Chemistry