Disruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast Genes

Agriculture & Biology

• induced mutation 100%
• mutation 55%
• yeasts 53%
• genome 44%
• single-stranded DNA 40%
• transcription initiation 30%
• genes 28%
• nucleotides 16%
• Petromyzon marinus 16%
• deamination 14%
• mutants 13%
• mutation rate 12%
• etiology 12%
• neoplasm cells 10%
• binding proteins 10%
• diploidy 9%
• inactivation 9%
• open reading frames 9%
• neoplasms 8%
• transcription (genetics) 8%
• clones 7%
• drugs 7%
• DNA 5%
• cells 3%

Earth & Environmental Sciences

• mutation 81%
• yeast 80%
• genome 76%
• gene 62%
• distribution 29%
• mutant 21%
• tumor 21%
• aid 19%
• protein 14%
• cell 12%
• etiology 12%
• subpopulation 11%
• clone 10%
• DNA 8%
• drug 8%
• exposure 5%
• sea 5%
• loss 5%
• effect 2%

Medicine & Life Sciences

• Yeasts 65%
• Genome 55%
• Mutation 45%
• Genes 32%
• APOBEC-1 Deaminase 21%
• APOBEC Deaminases 19%
• Petromyzon 19%
• Nucleotides 18%
• Deamination 15%
• Peptide Initiation Factors 14%
• Whole Genome Sequencing 13%
• Diploidy 12%
• Mutation Rate 12%
• Open Reading Frames 11%
• Cluster Analysis 10%
• Carrier Proteins 9%
• Clone Cells 9%
• Transcription Factors 8%
• Neoplasms 7%
• DNA 6%
• Pharmaceutical Preparations 4%