1 Scopus citations


Giant cell arteritis (GCA) is well known for its involvement of the proximal aorta and its branches, classically causing headache, visual impairment, and elevations in the erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP). We describe a case of biopsy-proven GCA initially presenting with limb claudication, oligoarticular inflammatory arthritis, and a positive antineutrophil cytoplasmic antibody with cytoplasmic staining (C-ANCA), treated successfully with a combination of prednisone and weekly methotrexate. This case illustrates the wide spectrum of features that can be seen with GCA, including the occasional presence of C-ANCA. The C-ANCA became negative after treatment.

Original languageEnglish (US)
Pages (from-to)216-218
Number of pages3
JournalJournal of Clinical Rheumatology
Issue number4
StatePublished - Aug 2005


  • Antineutrophil cytoplasm antibodies
  • Claudication
  • Giant cell arteritis
  • Inflammatory arthritis

ASJC Scopus subject areas

  • Rheumatology


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