Diverse mechanisms of BRAF inhibitor resistance in melanoma identified in clinical and preclinical studies

Medicine and Dentistry

• Akt Signaling 25%
• Alternative RNA Splicing 25%
• Cell Line 25%
• Cell Motility 25%
• Disease Exacerbation 50%
• Drug Sensitivity 25%
• Gene Expression 25%
• Gene Mutation 50%
• Glutamine 25%
• In Vitro 100%
• Melanoma Cell 25%
• Metastatic Melanoma 25%
• Mitogen-Activated Protein Kinase 50%
• Nodular Melanoma 100%
• Protein Tyrosine Kinase 50%
• Serine 25%
• Signal Transduction 25%
• Tumor Regression 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Clinical Study 100%
• Disease Exacerbation 100%
• Glutamine 50%
• Melanoma 100%
• Metastatic Melanoma 50%
• Preclinical Study 100%
• Protein Tyrosine Kinase 100%
• Serine 50%
• Tumor Regression 50%

Keyphrases

• BRAF Inhibitor Resistance 100%
• Serine Metabolism 25%