DNA methylation of viruses infecting a eukaryotic Chlorella-like green alga

James L. van Etten; Anne M. Schuster; Lois Girton; Dwight E. Burbank; David Swinton; Stanley Hattman

doi:10.1093/nar/13.10.3471

DNA methylation of viruses infecting a eukaryotic Chlorella-like green alga

James L. van Etten, Anne M. Schuster, Lois Girton, Dwight E. Burbank, David Swinton, Stanley Hattman

Plant Pathology

Research output: Contribution to journal › Article

55 Scopus citations

Abstract

The genomic DNAs of the eukaryotic Chlorella-like green alga, strain NC64A, and eleven of its viruses all contain significant levels of 5-methyldeoxycytidine. In addition, the host DNA as well as six of the viral DNAs also contain N⁶-methyldeoxyadenosine. At least some of the methylated bases in the host reside in different base sequences than the nethylated bases in the viruses as shown by differential susceptibility to restriction endonuclease enzymes. This suggests that the viruses encode for DNA methyltransferases with sequence specificities different from that of the host enzyme.

Original language	English (US)
Pages (from-to)	3471-3478
Number of pages	8
Journal	Nucleic acids research
Volume	13
Issue number	10
DOIs	https://doi.org/10.1093/nar/13.10.3471
State	Published - May 24 1985

ASJC Scopus subject areas

Genetics

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van Etten, J. L., Schuster, A. M., Girton, L., Burbank, D. E., Swinton, D., & Hattman, S. (1985). DNA methylation of viruses infecting a eukaryotic Chlorella-like green alga. Nucleic acids research, 13(10), 3471-3478. https://doi.org/10.1093/nar/13.10.3471

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