DNA polymorphism and molecular subtyping of the capsular gene cluster of group B Streptococcus

Shannon D. Manning, David W. Lacher, H. Dele Davies, Betsy Foxman, Thomas S. Whittam

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Serotyping and other phenotypic methods are often used to characterize the capsular polysaccharide of group B streptococci (GBS). We describe a capsular genotyping method that utilizes PCR of capsular polysaccharide synthesis genes (cps) and restriction enzyme digestion. This method facilitates the detection of DNA polymorphism in cps genes and correlates well with serotyping.

Original languageEnglish (US)
Pages (from-to)6113-6116
Number of pages4
JournalJournal of clinical microbiology
Volume43
Issue number12
DOIs
StatePublished - Dec 2005

ASJC Scopus subject areas

  • Microbiology (medical)

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