DNA sequencing of four bases using three lanes

Michael Nelson, James L. Van Etten, Reingard Grabherr

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


A three-lane DNA sequencing strategy Is described which is based on redundant binary coding principles from communications theory. Three-lane sequencing Is an efficient, accurate, and flexible strategy, suitable for large-scale automated DNA sequencing. Communications theory and algebraic coding principles can also be applied to sequencing other informational macromolecules.

Original languageEnglish (US)
Pages (from-to)1345-1348
Number of pages4
JournalNucleic acids research
Issue number6
StatePublished - Mar 25 1992

ASJC Scopus subject areas

  • Genetics

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