Doping-control urinalysis of a ginseng extract, Cold-FX®, in athletes

Danny P. Goel, Jonathan D. Geiger, Jacqueline J. Shan, Dean Kriellaars, Grant N. Pierce

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Nutraceuticals may induce doping infractions through contamination of the product itself or their ingestion might be metabolized within the body to create a positive doping control test. We tested this possibility using a commercially available, proprietary ginseng root extract (Cold-FX®, CV Technologies Inc., Edmonton, AB). After athletes ingested Cold-FX® for 28 d at 400 mg/d, urine samples were collected and processed under strict IOC doping control guidelines and then analyzed for a full screen of IOC banned/restricted substances by an IOC-approved laboratory. There were no positive tests for any banned substances in any of the subjects. Our study demonstrates that ingestion of Cold-FX® for 28 d at 400 mg/d does not represent a doping concern for athletes. Carefully controlled clinical studies like this one are necessary to provide the athlete, the nutraceutical industry and IOC regulatory bodies with information to avoid inadvertent exposure to banned/restricted or potentially unhealthy substances.

Original languageEnglish (US)
Pages (from-to)473-480
Number of pages8
JournalInternational Journal of Sport Nutrition and Exercise Metabolism
Issue number4
StatePublished - Aug 2004
Externally publishedYes


  • Athletic performance
  • Dietary supplements
  • Health foods
  • Natural health products
  • Nutraceuticals

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Orthopedics and Sports Medicine
  • Nutrition and Dietetics

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