Dutch translation, adaptation and validation of the OT-10 scale for orthostatic tremor

B. E.K.S. Swinnen, M. Bergers, W. A. Babeliowsky, D. Torres-Russotto, R. M.A. de Bie, A. F. van Rootselaar

Research output: Contribution to journalArticlepeer-review


Introduction: There are currently no effective treatments for primary orthostatic tremor (POT). An adequate disease-specific POT severity scale is a prerequisite to conduct clinical trials and monitor disease severity in clinical practice. Recently, the English OT-10 scale has been developed for this purpose. Here we aimed to obtain a scale to measure the severity of POT in Dutch speaking individuals. Methods: An established translation, adaptation and validation approach was employed to obtain a Dutch version of the OT-10 scale. Validation was performed in a Dutch POT cohort (n = 46). Results: A Dutch OT-10 scale was obtained which showed good internal consistency (Cronbach's alpha > 0.80), total score test–retest reliability (intraclass correlation coefficient > 0.80), and concurrent validity (Pearson correlation > 0.80). Item-to-total correlation was good (weighted kappa > 0.40) for all items, and item test–retest reliability was good (weighted kappa > 0.40) for eight out of ten items. Overall, the Dutch OT-10 scale demonstrated acceptable validity. Conclusions: We obtained and validated a Dutch version of the OT-10 scale, capturing POT severity. Next to its use in clinical practice, translation and validation of the OT-10 scale in more languages will help to find evidence-based treatments for POT.

Original languageEnglish (US)
Article number100200
JournalClinical Parkinsonism and Related Disorders
StatePublished - Jan 2023


  • Adaptation
  • Dutch translation
  • OT-10 scale
  • Orthostatic tremor
  • Validation

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience


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