Dyspnoea and the ovaries: A rare presentation of Krukenberg tumour

Wasiq Faraz Rawasia, Udit Chaddha, Karim El-Kersh, Rafael L. Perez

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Krukenberg tumour is a metastatic signet-ring adenocarcinoma of the ovary, usually with a gastrointestinal primary detected metachronously or synchronously. We present here a case of a 48 year-old woman who presented with a prolonged history of dyspnoea on exertion. Workup had revealed a pelvic mass. Thoracocentesis of her pleural effusion, with cytology, and pathology reports from her total abdominal hysterectomy with bilateral salpingooophorectomy revealed a carcinoma with signet-ring cells. Immunostains were positive for CDX2, CK7 and CK20, which was highly suggestive of a gastric primary. Colonoscopy was negative, and an oesophagogastroduodenoscopy revealed a few small crater ulcers, the biopsy of which was negative for cancer. A right-sided pleurodesis was performed for the unremitting malignant effusion, and a PleurX catheter was placed in her left pleural space. She was discharged home with a very poor prognosis.

Original languageEnglish (US)
Article number008302
JournalBMJ case reports
DOIs
StatePublished - 2013
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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