TY - JOUR
T1 - Early detection of cherubism with eventual bilateral progression
T2 - a literature review and case report
AU - Holley, Tyler J.
AU - Giannini, Peter J.
AU - Narayana, Nagamani
AU - Desa, Valmont P.
PY - 2019/3
Y1 - 2019/3
N2 - Cherubism is a rare familial disease of childhood that commonly affects the bilateral mandible and maxilla and typically resolves in adulthood. It has been shown to have a male predilection and has been mapped to the SH3 BP2 gene. Only 2 cases of unilateral cherubism have been documented in the literature; in the first case, the contralateral side was eventually affected. Although rare, unilateral cherubism presents a diagnostic dilemma. This case report describes a unique presentation of unilateral cherubism that progressed to affect the contralateral side and describes some of the considerations in the diagnosis and treatment of unilateral benign giant cell lesions of the jaws.
AB - Cherubism is a rare familial disease of childhood that commonly affects the bilateral mandible and maxilla and typically resolves in adulthood. It has been shown to have a male predilection and has been mapped to the SH3 BP2 gene. Only 2 cases of unilateral cherubism have been documented in the literature; in the first case, the contralateral side was eventually affected. Although rare, unilateral cherubism presents a diagnostic dilemma. This case report describes a unique presentation of unilateral cherubism that progressed to affect the contralateral side and describes some of the considerations in the diagnosis and treatment of unilateral benign giant cell lesions of the jaws.
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U2 - 10.1016/j.oooo.2018.08.011
DO - 10.1016/j.oooo.2018.08.011
M3 - Article
C2 - 30287203
AN - SCOPUS:85058455231
SN - 2212-4403
VL - 127
SP - e77-e83
JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
IS - 3
ER -