Early empiric antibiotic therapy for febrile neutropenia patients at low risk

K. V.I. Rolston, E. B. Rubenstein, A. Freifeld

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


Although it is apparent that certain patients with febrile neutropenic episodes can benefit from outpatient antibiotic therapy, not all low-risk patients are treated in this fashion. There are barriers, real and perceived, to implementing this approach for patients, health care providers, and caregivers. Table 3 summarizes the advantages and disadvantages of ambulatory management of febrile neutropenic patients. For many patients and physicians, outpatient oral antibiotics may be preferred, whereas for others a more conservative approach might be needed in order to feel comfortable with treating this population on an outpatient basis. In this situation, patients can be treated in a stepwise fashion as shown in Table 4. These alternatives allow physicians and patients options to discuss when planning treatment strategies for febrile neutropenia.

Original languageEnglish (US)
Pages (from-to)223-237
Number of pages15
JournalInfectious disease clinics of North America
Issue number2
StatePublished - 1996

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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