Eccrine syringofibroadenoma surrounding a squamous cell carcinoma: A case report

Subodh M. Lele; Elizabeth S. Gloster; Edward R. Heilman; Patrick C. Chen; Chun Kuo Chen; Archinto P. Anzil; Jason N. Pozner; Michael J. Reardon

doi:10.1111/j.1600-0560.1997.tb01576.x

Eccrine syringofibroadenoma surrounding a squamous cell carcinoma: A case report

Subodh M. Lele, Elizabeth S. Gloster, Edward R. Heilman, Patrick C. Chen, Chun Kuo Chen, Archinto P. Anzil, Jason N. Pozner, Michael J. Reardon

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

A 91-year-old man presented with a 9.0 x 7.0 cm exophytic mass on the dorsum of the right foot, surrounded by a scaling hyperkeratotic plaque-like lesion that had been present for many years. He had similar long-standing hyperkeratotic plaque-like lesions on both legs. Histopathologic examination of the exophytic mass revealed a well-differentiated squamous cell carcinoma surrounded by an eccrine syringofibroadenoma (ESFA). Histochemistry, immunohistochemistry and electron microscopy support this diagnosis. To our knowledge, this is the only reported case of ESFA being intimately associated with a malignant neoplasm.

Original language	English (US)
Pages (from-to)	193-196
Number of pages	4
Journal	Journal of Cutaneous Pathology
Volume	24
Issue number	3
DOIs	https://doi.org/10.1111/j.1600-0560.1997.tb01576.x
State	Published - 1997
Externally published	Yes

ASJC Scopus subject areas

Pathology and Forensic Medicine
Histology
Dermatology

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10.1111/j.1600-0560.1997.tb01576.x

Cite this

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title = "Eccrine syringofibroadenoma surrounding a squamous cell carcinoma: A case report",

abstract = "A 91-year-old man presented with a 9.0 x 7.0 cm exophytic mass on the dorsum of the right foot, surrounded by a scaling hyperkeratotic plaque-like lesion that had been present for many years. He had similar long-standing hyperkeratotic plaque-like lesions on both legs. Histopathologic examination of the exophytic mass revealed a well-differentiated squamous cell carcinoma surrounded by an eccrine syringofibroadenoma (ESFA). Histochemistry, immunohistochemistry and electron microscopy support this diagnosis. To our knowledge, this is the only reported case of ESFA being intimately associated with a malignant neoplasm.",

author = "Lele, {Subodh M.} and Gloster, {Elizabeth S.} and Heilman, {Edward R.} and Chen, {Patrick C.} and Chen, {Chun Kuo} and Anzil, {Archinto P.} and Pozner, {Jason N.} and Reardon, {Michael J.}",

year = "1997",

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T1 - Eccrine syringofibroadenoma surrounding a squamous cell carcinoma

T2 - A case report

AU - Lele, Subodh M.

AU - Gloster, Elizabeth S.

AU - Heilman, Edward R.

AU - Chen, Patrick C.

AU - Chen, Chun Kuo

AU - Anzil, Archinto P.

AU - Pozner, Jason N.

AU - Reardon, Michael J.

PY - 1997

Y1 - 1997

N2 - A 91-year-old man presented with a 9.0 x 7.0 cm exophytic mass on the dorsum of the right foot, surrounded by a scaling hyperkeratotic plaque-like lesion that had been present for many years. He had similar long-standing hyperkeratotic plaque-like lesions on both legs. Histopathologic examination of the exophytic mass revealed a well-differentiated squamous cell carcinoma surrounded by an eccrine syringofibroadenoma (ESFA). Histochemistry, immunohistochemistry and electron microscopy support this diagnosis. To our knowledge, this is the only reported case of ESFA being intimately associated with a malignant neoplasm.

AB - A 91-year-old man presented with a 9.0 x 7.0 cm exophytic mass on the dorsum of the right foot, surrounded by a scaling hyperkeratotic plaque-like lesion that had been present for many years. He had similar long-standing hyperkeratotic plaque-like lesions on both legs. Histopathologic examination of the exophytic mass revealed a well-differentiated squamous cell carcinoma surrounded by an eccrine syringofibroadenoma (ESFA). Histochemistry, immunohistochemistry and electron microscopy support this diagnosis. To our knowledge, this is the only reported case of ESFA being intimately associated with a malignant neoplasm.

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Eccrine syringofibroadenoma surrounding a squamous cell carcinoma: A case report

Abstract

ASJC Scopus subject areas

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