Edema disease-like brain lesions in gnotobiotic piglets infected with Escherichia coli serotype O157:H7

D. H. Francis, R. A. Moxley, C. Y. Andraos

Research output: Contribution to journalArticle

50 Scopus citations


Gnotobiotic piglets inoculated with Escherichia coli serotype O157:H7 strains that produced Shiga-like toxin II developed brain lesions similar to those observed in edema disease of swine, including arteriolar necrosis and malaria. Loss of ability to produce Shiga-like toxin II resulted in loss of ability to cause brain lesions.

Original languageEnglish (US)
Pages (from-to)1339-1342
Number of pages4
JournalInfection and immunity
Issue number4
StatePublished - Jan 1 1989


ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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