Abstract
Mouse embryos (4-8 cells) were cultured for 48 h in vitro in medium containing 1,4,6-androstatriene-3,17-dione (ATD). The inhibition of embryo development by ATD was overcome by oestradiol-17β but not by oestradiol-17α. Culture with ATD for the first and second 24 h led to normal numbers of blastocysts. The results show that preimplantation mouse embryos contain the enzymic machinery for synthesis of oestrogen.
Original language | English (US) |
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Pages (from-to) | 63-66 |
Number of pages | 4 |
Journal | Journal of reproduction and fertility |
Volume | 66 |
Issue number | 1 |
DOIs | |
State | Published - 1982 |
Externally published | Yes |
ASJC Scopus subject areas
- Physiology
- Embryology
- Molecular Biology
- Obstetrics and Gynecology
- Developmental Biology