Effect of critical care pharmacist's intervention on medication errors: A systematic review and meta-analysis of observational studies

Tiansheng Wang, Neal Benedict, Keith M. Olsen, Rong Luan, Xi Zhu, Ningning Zhou, Huilin Tang, Yingying Yan, Yao Peng, Luwen Shi

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Pharmacists are integral members of the multidisciplinary team for critically ill patients. Multiple nonrandomized controlled studies have evaluated the outcomes of pharmacist interventions in the intensive care unit (ICU). This systematic review focuses on controlled clinical trials evaluating the effect of pharmacist intervention on medication errors (MEs) in ICU settings. Two independent reviewers searched Medline, Embase, and Cochrane databases. The inclusion criteria were nonrandomized controlled studies that evaluated the effect of pharmacist services vs no intervention on ME rates in ICU settings. Four studies were included in the meta-analysis. Results suggest that pharmacist intervention has no significant contribution to reducing general MEs, although pharmacist intervention may significantly reduce preventable adverse drug events and prescribing errors. This meta-analysis highlights the need for high-quality studies to examine the effect of the critical care pharmacist.

Original languageEnglish (US)
Pages (from-to)1101-1106
Number of pages6
JournalJournal of Critical Care
Volume30
Issue number5
DOIs
StatePublished - Oct 1 2015

Keywords

  • Critical care
  • Intensive care unit
  • Medication error
  • Meta-analysis
  • Pharmaceutical care
  • Pharmacist intervention

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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