Effect of glycerol on some kinetic parameters of phosphorylase b

Sandor Damjanovich; Judit Bot; Bela Somogyi; Janos Sümegi

doi:10.1016/0005-2744(72)90072-1

Effect of glycerol on some kinetic parameters of phosphorylase b

Sandor Damjanovich, Judit Bot, Bela Somogyi, Janos Sümegi

Pathology & Microbiology

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Abstract

The effect of different glycerol concentrations upon the activity and allosteric regulation of phosphorylase b has been studied. Glycerol increased the apparent K_m of the allosteric regulator and decreased the V of the enzyme. The enzyme activity was reduced by glycerol, according to the temperature, similar to the effect of decreasing the concentration of AMP.

Original language	English (US)
Pages (from-to)	345-348
Number of pages	4
Journal	BBA - Enzymology
Volume	284
Issue number	1
DOIs	https://doi.org/10.1016/0005-2744(72)90072-1
State	Published - Sep 19 1972

ASJC Scopus subject areas

Medicine(all)

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10.1016/0005-2744(72)90072-1

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title = "Effect of glycerol on some kinetic parameters of phosphorylase b",

abstract = "The effect of different glycerol concentrations upon the activity and allosteric regulation of phosphorylase b has been studied. Glycerol increased the apparent Km of the allosteric regulator and decreased the V of the enzyme. The enzyme activity was reduced by glycerol, according to the temperature, similar to the effect of decreasing the concentration of AMP.",

author = "Sandor Damjanovich and Judit Bot and Bela Somogyi and Janos S{\"u}megi",

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AU - Damjanovich, Sandor

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AU - Somogyi, Bela

AU - Sümegi, Janos

PY - 1972/9/19

Y1 - 1972/9/19

N2 - The effect of different glycerol concentrations upon the activity and allosteric regulation of phosphorylase b has been studied. Glycerol increased the apparent Km of the allosteric regulator and decreased the V of the enzyme. The enzyme activity was reduced by glycerol, according to the temperature, similar to the effect of decreasing the concentration of AMP.

AB - The effect of different glycerol concentrations upon the activity and allosteric regulation of phosphorylase b has been studied. Glycerol increased the apparent Km of the allosteric regulator and decreased the V of the enzyme. The enzyme activity was reduced by glycerol, according to the temperature, similar to the effect of decreasing the concentration of AMP.

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Effect of glycerol on some kinetic parameters of phosphorylase b

Abstract

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