Effect of low intravaginal doses of prostaglandin E2 on the closure time of the ductus arteriosus in term newborn infants

David A. Danford, William F. Rayburn, Ann M. Miller, Gary L. Felix, Mary E. Bussey

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Seventeen term newborn infants (control subjects) and 17 whose mothers had been given intravaginal doses of postaglandin E2 (PGE2) were examined serially by color Doppler echocardiography to determine whether maternal PGE2 prolonged ductal patency. No clinically relevant differences in closure times were found. Low-dose intravaginal PGE2 therapy was not associated with prolonged ductal patency in term infants.

Original languageEnglish (US)
Pages (from-to)632-634
Number of pages3
JournalThe Journal of Pediatrics
Volume122
Issue number4
DOIs
StatePublished - Apr 1993

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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