Abstract
Purpose: This study examines the impact of corneal surface lubricants used during pars plana vitrectomy on corneal edema. Methods: This prospective, observational, clinical study occurred at an academic institution. Participants were individuals aged 18 years and older who had already consented to undergo pars plana vitrectomy, without pre-existing corneal pathology. A corneal lubricant was chosen by the surgeon. Corneal thickness was measured preoperatively and postoperatively using pachymetry and anterior segment optical coherence tomography (AS-OCT). Main outcome measure was change in corneal thickness as measured by pachymetry. Results: Forty-one patients completed the study protocol. The 23 subjects in the SHCS group had a significantly smaller increase in corneal thickness as measured by pachymetry compared with the 18 subjects in the HPMC group (29.9 mm vs. 58.1 mm, P value 0.02). When measured by anterior segment optical coherence tomography, the SHCS group had a smaller increase in corneal thickness compared with the HPMC group (0.04 mm vs. 0.06 mm, P value 0.09) but did not reach significance. Conclusion: SHCS is associated with reduced postoperative increase in corneal pachymetry as compared to HPMC.
Original language | English (US) |
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Pages (from-to) | 1616-1622 |
Number of pages | 7 |
Journal | Retina |
Volume | 40 |
Issue number | 8 |
DOIs | |
State | Published - Aug 1 2020 |
Externally published | Yes |
Keywords
- Corneal edema
- Corneal surface lubricants
- Pars plana vitrectomy
- Surgical technique
ASJC Scopus subject areas
- Ophthalmology