Effect of macrophage activators on the phagocytosis of mycobacteria by Schwann cells

Hamid Band, G. P. Talwar

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Concanavalin A-induced lymphokines decreased the phagocytosis of 14C- acetate-labelled Mycobacterium w by 33B rat Schwannoma cells while increasing the phagocytosis by macrophages. This suggests that Schwann cells are responsive to lymphokines. Phorbol myristate acetate decreased the phagocytosis in Schwannoma cells but increased that in macrophages. Schwann cells, thus, respond to stimulants of macrophage phagocytosis in a manner opposite to that of macrophages.

Original languageEnglish (US)
Pages (from-to)109-113
Number of pages5
JournalJournal of Neuroimmunology
Volume13
Issue number1
DOIs
StatePublished - Nov 1986
Externally publishedYes

Keywords

  • Lymphokines
  • Macrophage activators
  • Mycobacteria
  • Phagocytosis
  • Schwann cells

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Neurology
  • Clinical Neurology

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