Effect of spinal cord transection on plasma and hepatic levels of certain essential elements and vitamins in rats

Anthony J. Barak; Victor A. Medina; Richard J. Kemmy; Michael F. Sorrell

doi:10.1016/S0271-5317(81)80055-3

Effect of spinal cord transection on plasma and hepatic levels of certain essential elements and vitamins in rats

Anthony J. Barak, Victor A. Medina, Richard J. Kemmy, Michael F. Sorrell

Research output: Contribution to journal › Article › peer-review

Abstract

This study was conducted to determine whether spinal cord transection produces nutritional deficiency states in certain essential elements and water soluble vitamins in the rat. Spinal cords of female rats were severed at the T-9 level and these animals were matched and pair-fed to control animals that had undergone sham surgery. Following periods of 60, 90 and 180 days, animals were sacrificed and their plasma and livers assayed for selenium, manganese, zinc and magnesium and eight water soluble vitamins. The results indicate that spinal cord injury did not cause deficiencees in those nutrients studied. Instead the cord transection produced accumulations in the liver of all the elements and six of the vitamins studied. No explanation for these accumulations is known at this time.

Original language	English (US)
Pages (from-to)	519-524
Number of pages	6
Journal	Nutrition Research
Volume	1
Issue number	5
DOIs	https://doi.org/10.1016/S0271-5317(81)80055-3
State	Published - 1981

Keywords

elements
rats
spinal cord injury
vitamins

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Nutrition and Dietetics

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10.1016/S0271-5317(81)80055-3

Cite this

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title = "Effect of spinal cord transection on plasma and hepatic levels of certain essential elements and vitamins in rats",

abstract = "This study was conducted to determine whether spinal cord transection produces nutritional deficiency states in certain essential elements and water soluble vitamins in the rat. Spinal cords of female rats were severed at the T-9 level and these animals were matched and pair-fed to control animals that had undergone sham surgery. Following periods of 60, 90 and 180 days, animals were sacrificed and their plasma and livers assayed for selenium, manganese, zinc and magnesium and eight water soluble vitamins. The results indicate that spinal cord injury did not cause deficiencees in those nutrients studied. Instead the cord transection produced accumulations in the liver of all the elements and six of the vitamins studied. No explanation for these accumulations is known at this time.",

keywords = "elements, rats, spinal cord injury, vitamins",

author = "Barak, {Anthony J.} and Medina, {Victor A.} and Kemmy, {Richard J.} and Sorrell, {Michael F.}",

note = "Funding Information: *This research was partially supported by a grant from the Technology and Research Foundation of the Paralyzed Veterans of America.",

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T1 - Effect of spinal cord transection on plasma and hepatic levels of certain essential elements and vitamins in rats

AU - Barak, Anthony J.

AU - Medina, Victor A.

AU - Kemmy, Richard J.

AU - Sorrell, Michael F.

N1 - Funding Information: *This research was partially supported by a grant from the Technology and Research Foundation of the Paralyzed Veterans of America.

PY - 1981

Y1 - 1981

N2 - This study was conducted to determine whether spinal cord transection produces nutritional deficiency states in certain essential elements and water soluble vitamins in the rat. Spinal cords of female rats were severed at the T-9 level and these animals were matched and pair-fed to control animals that had undergone sham surgery. Following periods of 60, 90 and 180 days, animals were sacrificed and their plasma and livers assayed for selenium, manganese, zinc and magnesium and eight water soluble vitamins. The results indicate that spinal cord injury did not cause deficiencees in those nutrients studied. Instead the cord transection produced accumulations in the liver of all the elements and six of the vitamins studied. No explanation for these accumulations is known at this time.

AB - This study was conducted to determine whether spinal cord transection produces nutritional deficiency states in certain essential elements and water soluble vitamins in the rat. Spinal cords of female rats were severed at the T-9 level and these animals were matched and pair-fed to control animals that had undergone sham surgery. Following periods of 60, 90 and 180 days, animals were sacrificed and their plasma and livers assayed for selenium, manganese, zinc and magnesium and eight water soluble vitamins. The results indicate that spinal cord injury did not cause deficiencees in those nutrients studied. Instead the cord transection produced accumulations in the liver of all the elements and six of the vitamins studied. No explanation for these accumulations is known at this time.

KW - elements

KW - rats

KW - spinal cord injury

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ER -

Effect of spinal cord transection on plasma and hepatic levels of certain essential elements and vitamins in rats

Abstract

Keywords

ASJC Scopus subject areas

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