Effect of spinal cord transection on plasma and hepatic levels of certain essential elements and vitamins in rats

Anthony J. Barak, Victor A. Medina, Richard J. Kemmy, Michael F. Sorrell

Research output: Contribution to journalArticle

Abstract

This study was conducted to determine whether spinal cord transection produces nutritional deficiency states in certain essential elements and water soluble vitamins in the rat. Spinal cords of female rats were severed at the T-9 level and these animals were matched and pair-fed to control animals that had undergone sham surgery. Following periods of 60, 90 and 180 days, animals were sacrificed and their plasma and livers assayed for selenium, manganese, zinc and magnesium and eight water soluble vitamins. The results indicate that spinal cord injury did not cause deficiencees in those nutrients studied. Instead the cord transection produced accumulations in the liver of all the elements and six of the vitamins studied. No explanation for these accumulations is known at this time.

Original languageEnglish (US)
Pages (from-to)519-524
Number of pages6
JournalNutrition Research
Volume1
Issue number5
DOIs
StatePublished - 1981

Keywords

  • elements
  • rats
  • spinal cord injury
  • vitamins

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Nutrition and Dietetics

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