Effectiveness of low-dose radiation for primary cutaneous anaplastic large cell lymphoma

Grace L. Smith, Madeleine Duvic, Zeinab Abou Yehia, Pamela Allen, Naveen Garg, Tina Suki, Sarah A. Milgrom, Chelsea C. Pinnix, Yasuhiro Oki, Joseph D. Khoury, Bouthaina S. Dabaja

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Primary cutaneous anaplastic large cell lymphoma (pcALCL) is conventionally treated with radiation therapy (RT) doses ≥30 Gy. In a series of 21 patients with pcALCL, responses were examined after a range of RT doses: ≤20 Gy, 20 to 29 Gy, and ≥30 Gy. Three-year freedom from local relapse was 100%, 86%, and 100%, respectively (P = .28). Low-dose RT appeared to be an acceptable approach for local control in the setting of the indolent, chronic course of pcALCL in this series.

Original languageEnglish (US)
Pages (from-to)363-369
Number of pages7
JournalAdvances in Radiation Oncology
Volume2
Issue number3
DOIs
StatePublished - Jul 2017
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

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