Endoscopy in the diagnosis of gastrointestinal mycobacterium avium-intracellulare infection

Howard P. Monsour; Eamonn M.M. Quigley; Rodney S. Markin; Douglas D. Dalke; Jonathan C. Goldsmith; Richard F. Harty

doi:10.1097/00004836-199102000-00007

Endoscopy in the diagnosis of gastrointestinal mycobacterium avium-intracellulare infection

Howard P. Monsour, Eamonn M.M. Quigley, Rodney S. Markin, Douglas D. Dalke, Jonathan C. Goldsmith, Richard F. Harty

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Two cases of mycobacterium avium-intracellulare (MAI) infection in association with acquired immunodeficiency syndrome (AIDS) are presented to highlight the distinctive upper gastrointestinal endoscopic appearances: 2x4 mm diameter, white nodules with intervening erythema and hemorrhagic erosions covered the mucosa of the second part of the duodenum. Histological evaluation of these nodules revealed diffuse expansion of the lamina propria by macrophages that contained numerous intracellular and extracellular acid-fast organisms. We conclude that endoscopy with endoscopic biopsy may represent the most rapid and sensitive diagnostic tool available in this disease.

Original language	English (US)
Pages (from-to)	20-24
Number of pages	5
Journal	Journal of Clinical Gastroenterology
Volume	13
Issue number	1
DOIs	https://doi.org/10.1097/00004836-199102000-00007
State	Published - Feb 1991

Keywords

AIDS
Duodenum
Endoscopy
Malabsorption
Mycobacterium avium-intracellulare
Whipples disease

ASJC Scopus subject areas

Gastroenterology

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10.1097/00004836-199102000-00007

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title = "Endoscopy in the diagnosis of gastrointestinal mycobacterium avium-intracellulare infection",

abstract = "Two cases of mycobacterium avium-intracellulare (MAI) infection in association with acquired immunodeficiency syndrome (AIDS) are presented to highlight the distinctive upper gastrointestinal endoscopic appearances: 2x4 mm diameter, white nodules with intervening erythema and hemorrhagic erosions covered the mucosa of the second part of the duodenum. Histological evaluation of these nodules revealed diffuse expansion of the lamina propria by macrophages that contained numerous intracellular and extracellular acid-fast organisms. We conclude that endoscopy with endoscopic biopsy may represent the most rapid and sensitive diagnostic tool available in this disease.",

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AU - Monsour, Howard P.

AU - Quigley, Eamonn M.M.

AU - Markin, Rodney S.

AU - Dalke, Douglas D.

AU - Goldsmith, Jonathan C.

AU - Harty, Richard F.

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N2 - Two cases of mycobacterium avium-intracellulare (MAI) infection in association with acquired immunodeficiency syndrome (AIDS) are presented to highlight the distinctive upper gastrointestinal endoscopic appearances: 2x4 mm diameter, white nodules with intervening erythema and hemorrhagic erosions covered the mucosa of the second part of the duodenum. Histological evaluation of these nodules revealed diffuse expansion of the lamina propria by macrophages that contained numerous intracellular and extracellular acid-fast organisms. We conclude that endoscopy with endoscopic biopsy may represent the most rapid and sensitive diagnostic tool available in this disease.

AB - Two cases of mycobacterium avium-intracellulare (MAI) infection in association with acquired immunodeficiency syndrome (AIDS) are presented to highlight the distinctive upper gastrointestinal endoscopic appearances: 2x4 mm diameter, white nodules with intervening erythema and hemorrhagic erosions covered the mucosa of the second part of the duodenum. Histological evaluation of these nodules revealed diffuse expansion of the lamina propria by macrophages that contained numerous intracellular and extracellular acid-fast organisms. We conclude that endoscopy with endoscopic biopsy may represent the most rapid and sensitive diagnostic tool available in this disease.

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KW - Duodenum

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KW - Malabsorption

KW - Mycobacterium avium-intracellulare

KW - Whipples disease

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Endoscopy in the diagnosis of gastrointestinal mycobacterium avium-intracellulare infection

Abstract

Keywords

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