Enhanced coherent anti-Stokes Raman scattering imaging using silica mircospheres

X. Huang, X. N. He, W. Xiong, Y. Gao, L. J. Jiang, L. Liu, Y. S. Zhou, J. F. Silvain, L. Jiang, Y. F. Lu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

A technique was developed to achieve enhanced coherent anti-Stokes Raman scattering (CARS) imaging using selfassembled silica microspheres. In this study, a layer of optically transparent silica microspheres was self-assembled onto polymer grating samples to enhance the CARS signals. The highest enhancement of 12.5 was achieved using 6.1-μmdiameter microspheres for C-H molecule vibration. Finite-difference time-domain (FDTD) algorithm under the perfectly matched layer boundary condition was used to simulate the enhancement using silica microspheres of different diameters.

Original languageEnglish (US)
Title of host publicationNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI
PublisherSPIE
ISBN (Print)9780819498670
DOIs
StatePublished - 2014
EventNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI - San Francisco, CA, United States
Duration: Feb 3 2014Feb 6 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8954
ISSN (Print)1605-7422

Conference

ConferenceNanoscale Imaging, Sensing, and Actuation for Biomedical Applications XI
Country/TerritoryUnited States
CitySan Francisco, CA
Period2/3/142/6/14

Keywords

  • Enhanced Coherent anti-Stokes Raman scattering
  • FDTD simulation
  • silica microspheres

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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