Enhanced competitiveness of tomato bushy stunt virus defective interfering RNAs by segment duplication or nucleotide insertion

K. Andrew White, T. Jack Morris

Research output: Contribution to journalComment/debatepeer-review

27 Scopus citations

Abstract

We have analyzed atypical tomato bushy stunt virus defective interfering (DI) RNA species which accumulated during a passage series in protoplasts. We present a rationale for the order of appearance of these molecules and show, using competition assays, that either segment duplication or single nucleotide insertion can enhance DI RNA competitiveness. Possible mechanisms for the introduction of the modifications observed in these DI RNAs are discussed.

Original languageEnglish (US)
Pages (from-to)6092-6096
Number of pages5
JournalJournal of virology
Volume68
Issue number9
DOIs
StatePublished - Sep 1994

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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