Mice were treated with ketoconazole with and without dimethyl sulfoxide. Concentrations of ketoconazole at 3 and 5 h after treatment were significantly higher in serum (P < 0.05) and brain tissue homogenate (P < 0.01) of mice treated with dimethyl sulfoxide than in those of mice not treated with diemthyl sulfoxide.
|Original language||English (US)|
|Number of pages||2|
|Journal||Antimicrobial Agents and Chemotherapy|
|State||Published - 1986|
ASJC Scopus subject areas
- Pharmacology (medical)
- Infectious Diseases