TY - JOUR
T1 - Enhancing recruitment and retention in randomized clinical trials of cancer symptom management.
AU - Berger, Ann M.
AU - Neumark, Donna Edwards
AU - Chamberlain, Julie
PY - 2007/3
Y1 - 2007/3
N2 - PURPOSE/OBJECTIVES: To describe techniques to overcome challenges of collaborating with multiple clinical sites and participants to enhance recruitment and retention for cancer symptom management randomized clinical trials (RCTs). DATA SOURCES: Personal experiences and publications related to recruitment and retention of sites and participants in RCTs, which were found by searching MEDLINE, CINAHL, and PsycINFO records. DATA SYNTHESIS: Techniques to overcome challenges related to multisite research, patient confidentiality guidelines, and work with an at-risk population were identified and applied successfully in an RCT designed to modify fatigue during and following adjuvant breast cancer chemotherapy. CONCLUSIONS: Successful recruitment and retention depended on the value that site personnel placed on symptom management research, identification of a designated contact person at each site, and flexibility in maintaining communication among the project director, contact individuals, and participants. IMPLICATIONS FOR NURSING: Initial and ongoing collaboration with participants and a contact person at each site, assurance of privacy of protected health information, and emotional support are critical to recruitment and retention throughout cancer symptom management RCTs.
AB - PURPOSE/OBJECTIVES: To describe techniques to overcome challenges of collaborating with multiple clinical sites and participants to enhance recruitment and retention for cancer symptom management randomized clinical trials (RCTs). DATA SOURCES: Personal experiences and publications related to recruitment and retention of sites and participants in RCTs, which were found by searching MEDLINE, CINAHL, and PsycINFO records. DATA SYNTHESIS: Techniques to overcome challenges related to multisite research, patient confidentiality guidelines, and work with an at-risk population were identified and applied successfully in an RCT designed to modify fatigue during and following adjuvant breast cancer chemotherapy. CONCLUSIONS: Successful recruitment and retention depended on the value that site personnel placed on symptom management research, identification of a designated contact person at each site, and flexibility in maintaining communication among the project director, contact individuals, and participants. IMPLICATIONS FOR NURSING: Initial and ongoing collaboration with participants and a contact person at each site, assurance of privacy of protected health information, and emotional support are critical to recruitment and retention throughout cancer symptom management RCTs.
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U2 - 10.1188/07.ONF.E17-E22
DO - 10.1188/07.ONF.E17-E22
M3 - Article
C2 - 17573292
AN - SCOPUS:34548405501
SN - 0190-535X
VL - 34
SP - E17-22
JO - Oncology nursing forum
JF - Oncology nursing forum
IS - 2
ER -