Abstract
Gout is the most prevalent type of inflammatory arthritis worldwide and environmental factors contribute to hyperuricemia and risk for gout flare. Causes of hyperuricemia include increased purine consumption from meat, alcohol, and high fructose corn syrup as well as medications such as cyclosporine, low-dose aspirin, or diuretics. Triggers for gout flares include increased purine consumption and medication use such as urate lowering therapy and diuretics. Environmental exposures including lead exposure, particulate matter exposure, temperature fluctuations, and physiologic stress have been found to trigger flares. In the right clinical scenario, these factors should be considered when treating gout patients.
Original language | English (US) |
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Pages (from-to) | 891-906 |
Number of pages | 16 |
Journal | Rheumatic Disease Clinics of North America |
Volume | 48 |
Issue number | 4 |
DOIs | |
State | Published - Nov 2022 |
Keywords
- Diet
- Environmental exposures
- Epidemiology
- Gout
- Hyperuricemia
ASJC Scopus subject areas
- Rheumatology