TY - JOUR
T1 - Epidemiologic profile of pediatric brain tumors in Morocco
AU - Karkouri, Mehdi
AU - Zafad, Sadia
AU - Khattab, Mohammed
AU - Benjaafar, Noureddine
AU - El Kacemi, Hanan
AU - Sefiani, Sana
AU - Kettani, Fouad
AU - Dey, Subhojit
AU - Soliman, Amr S.
N1 - Funding Information:
Funding Leana May was supported by a fellowship from the Cancer Epidemiology Education in Special Populations Program of the University of Michigan (R25 CA112383) from the National Cancer Institute.
PY - 2010/8
Y1 - 2010/8
N2 - Introduction: Brain tumors are the most common solid tumors diagnosed among children below 15 years worldwide. However, little is known about the profile of pediatric brain tumors in Africa. The purpose of this study was to further elaborate the epidemiological profile of pediatric brain tumors in Africa, specifically Morocco. Methods: A retrospective review was conducted of all patients with primary brain tumors in the age group 0-19 years, from 2003 to 2007, from multiple centers in two cities of Rabat and Casablanca, Morocco. Only patients with histopathological confirmation were included (n∈=∈542). Descriptive epidemiologic profiles were created for the patients by age, sex, and histological subtypes of brain tumors. Results: Overall medulloblastoma was the most common brain tumor (34.5%), followed by pilocytic astrocytoma (17.3%) and diffuse astrocytoma grade 2 (12.5%). Brain tumors occurred most commonly in 5-9-year age group followed by 10-14-year age group with the former being more common among males and the latter being more common among females. We also found medulloblastoma to be the most common brain tumor in the 0-14-year-olds. Conclusions: In this rare study focused on pediatric brain tumors in Morocco, most of the findings were consistent with past studies from other parts of the world. However, we found medulloblastoma to be the most common pediatric brain tumor followed by astrocytoma.
AB - Introduction: Brain tumors are the most common solid tumors diagnosed among children below 15 years worldwide. However, little is known about the profile of pediatric brain tumors in Africa. The purpose of this study was to further elaborate the epidemiological profile of pediatric brain tumors in Africa, specifically Morocco. Methods: A retrospective review was conducted of all patients with primary brain tumors in the age group 0-19 years, from 2003 to 2007, from multiple centers in two cities of Rabat and Casablanca, Morocco. Only patients with histopathological confirmation were included (n∈=∈542). Descriptive epidemiologic profiles were created for the patients by age, sex, and histological subtypes of brain tumors. Results: Overall medulloblastoma was the most common brain tumor (34.5%), followed by pilocytic astrocytoma (17.3%) and diffuse astrocytoma grade 2 (12.5%). Brain tumors occurred most commonly in 5-9-year age group followed by 10-14-year age group with the former being more common among males and the latter being more common among females. We also found medulloblastoma to be the most common brain tumor in the 0-14-year-olds. Conclusions: In this rare study focused on pediatric brain tumors in Morocco, most of the findings were consistent with past studies from other parts of the world. However, we found medulloblastoma to be the most common pediatric brain tumor followed by astrocytoma.
KW - Africa
KW - Central nervous system
KW - Descriptive epidemiology
KW - Morocco
KW - Pediatric brain tumors
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U2 - 10.1007/s00381-010-1097-y
DO - 10.1007/s00381-010-1097-y
M3 - Article
C2 - 20179946
AN - SCOPUS:77956192204
SN - 0256-7040
VL - 26
SP - 1021
EP - 1027
JO - Child's Nervous System
JF - Child's Nervous System
IS - 8
ER -