Epidemiology and diagnosis of health care - Associated infections in the NICU

Richard A. Polin; Susan Denson; Michael T. Brady; Lu Ann Papile; Jill E. Baley; Waldemar A. Carlo; James J. Cummings; Praveen Kumar; Rosemarie C. Tan; Kristi L. Watterberg; Wanda D. Barfield; Ann L. Jefferies; George A. Macones; Rosalie O. Mainous; Tonse N.K. Raju; Kasper S. Wang; Jim Couto; Carrie L. Byington; H. Dele Davies; Kathryn M. Edwards; Mary P. Glode; Mary Anne Jackson; Harry L. Keyserling; Yvonne A. Maldonado; Dennis L. Murray; Walter A. Orenstein; Gordon E. Schutze; Rodney E. Willoughby; Theoklis E. Zaoutis; Marc A. Fischer; Bruce Gellin; Richard L. Gorman; Lucia Lee; R. Douglas Pratt; Jennifer S. Read; Joan Robinson; Marco Aurelio Palazzi Safadi; Jane Seward; Jeffrey R. Starke; Geoffrey Simon; Tina Q. Tan; Carol J. Baker; Henry H. Bernstein; David W. Kimberlin; Sarah S. Long; H. Cody Meissner; Larry K. Pickering; Lorry G. Rubin; Jennifer Frantz

doi:10.1542/peds.2012-0147

Epidemiology and diagnosis of health care - Associated infections in the NICU

Richard A. Polin, Susan Denson, Michael T. Brady, Lu Ann Papile, Jill E. Baley, Waldemar A. Carlo, James J. Cummings, Praveen Kumar, Rosemarie C. Tan, Kristi L. Watterberg, Wanda D. Barfield, Ann L. Jefferies, George A. Macones, Rosalie O. Mainous, Tonse N.K. Raju, Kasper S. Wang, Jim Couto, Carrie L. Byington, H. Dele Davies, Kathryn M. EdwardsMary P. Glode, Mary Anne Jackson, Harry L. Keyserling, Yvonne A. Maldonado, Dennis L. Murray, Walter A. Orenstein, Gordon E. Schutze, Rodney E. Willoughby, Theoklis E. Zaoutis, Marc A. Fischer, Bruce Gellin, Richard L. Gorman, Lucia Lee, R. Douglas Pratt, Jennifer S. Read, Joan Robinson, Marco Aurelio Palazzi Safadi, Jane Seward, Jeffrey R. Starke, Geoffrey Simon, Tina Q. Tan, Carol J. Baker, Henry H. Bernstein, David W. Kimberlin, Sarah S. Long, H. Cody Meissner, Larry K. Pickering, Lorry G. Rubin, Jennifer Frantz

Research output: Contribution to journal › Article › peer-review

93 Scopus citations

Abstract

Health care-associated infections in the NICU are a major clinical problem resulting in increased morbidity and mortality, prolonged length of hospital stays, and increased medical costs. Neonates are at high risk for health care-associated infections because of impaired host defense mechanisms, limited amounts of protective endogenous flora on skin and mucosal surfaces at time of birth, reduced barrier function of neonatal skin, the use of invasive procedures and devices, and frequent exposure to broad-spectrum antibiotics. This statement will review the epidemiology and diagnosis of health care-associated infections in newborn infants.

Original language	English (US)
Pages (from-to)	e1104-e1109
Journal	Pediatrics
Volume	129
Issue number	4
DOIs	https://doi.org/10.1542/peds.2012-0147
State	Published - Apr 2012
Externally published	Yes

Keywords

Antibiotics
Health care-associated infection
NICU
Neonate
Newborn
Nosocomial infection

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1542/peds.2012-0147

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Polin, R. A., Denson, S., Brady, M. T., Papile, L. A., Baley, J. E., Carlo, W. A., Cummings, J. J., Kumar, P., Tan, R. C., Watterberg, K. L., Barfield, W. D., Jefferies, A. L., Macones, G. A., Mainous, R. O., Raju, T. N. K., Wang, K. S., Couto, J., Byington, C. L., Davies, H. D., ... Frantz, J. (2012). Epidemiology and diagnosis of health care - Associated infections in the NICU. Pediatrics, 129(4), e1104-e1109. https://doi.org/10.1542/peds.2012-0147

Polin, RA, Denson, S, Brady, MT, Papile, LA, Baley, JE, Carlo, WA, Cummings, JJ, Kumar, P, Tan, RC, Watterberg, KL, Barfield, WD, Jefferies, AL, Macones, GA, Mainous, RO, Raju, TNK, Wang, KS, Couto, J, Byington, CL, Davies, HD, Edwards, KM, Glode, MP, Jackson, MA, Keyserling, HL, Maldonado, YA, Murray, DL, Orenstein, WA, Schutze, GE, Willoughby, RE, Zaoutis, TE, Fischer, MA, Gellin, B, Gorman, RL, Lee, L, Pratt, RD, Read, JS, Robinson, J, Safadi, MAP, Seward, J, Starke, JR, Simon, G, Tan, TQ, Baker, CJ, Bernstein, HH, Kimberlin, DW, Long, SS, Meissner, HC, Pickering, LK, Rubin, LG & Frantz, J 2012, 'Epidemiology and diagnosis of health care - Associated infections in the NICU', Pediatrics, vol. 129, no. 4, pp. e1104-e1109. https://doi.org/10.1542/peds.2012-0147

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abstract = "Health care-associated infections in the NICU are a major clinical problem resulting in increased morbidity and mortality, prolonged length of hospital stays, and increased medical costs. Neonates are at high risk for health care-associated infections because of impaired host defense mechanisms, limited amounts of protective endogenous flora on skin and mucosal surfaces at time of birth, reduced barrier function of neonatal skin, the use of invasive procedures and devices, and frequent exposure to broad-spectrum antibiotics. This statement will review the epidemiology and diagnosis of health care-associated infections in newborn infants.",

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AU - Cummings, James J.

AU - Kumar, Praveen

AU - Tan, Rosemarie C.

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AU - Safadi, Marco Aurelio Palazzi

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Epidemiology and diagnosis of health care - Associated infections in the NICU

Abstract

Keywords

ASJC Scopus subject areas

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