Epithelioid sarcoma-like (pseudomyogenic) hemangioendothelioma, clinically mimicking dermatofibroma, diagnosed by skin biopsy in a 30-year-old man

Lauren N. Stuart, Jerad M. Gardner, Scott R. Lauer, David K. Monson, Douglas C. Parker, Mark A. Edgar

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Epithelioid sarcoma-like (pseudomyogenic) hemangioendothelioma (ESHE) represents a rare soft tissue and bone tumor that typically presents as nodule(s) in the distal extremities of young adults. The nodules traverse several tissue planes simultaneously and can involve the dermis, subcutis, skeletal muscle and bone. ESHE shares clinical and microscopic features with epithelioid sarcoma (ES), and, accordingly, is commonly misdiagnosed as ES. However, unlike ES, which has a poor prognosis, ESHE commonly follows an indolent course. Herein, we report a case of ESHE diagnosed by skin biopsy that clinically mimicked a dermatofibroma. We also provide clinical photographs of the lesions in various stages of development, representing information that has not been previously published, to our knowledge.

Original languageEnglish (US)
Pages (from-to)909-913
Number of pages5
JournalJournal of Cutaneous Pathology
Volume40
Issue number10
DOIs
StatePublished - Oct 2013

Keywords

  • hemangioendothelioma
  • leg tumor
  • pseudomyogenic
  • soft tissue tumor

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology
  • Dermatology

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