Abstract
Nanofibre forming peptide amphiphiles were conjugated to naproxen through an esterase-sensitive linker. The amount of naproxen released, in the presence of enzymes, was influenced by the linker conjugating the drug to the supramolecular assembly. In vitro studies showed the anti-inflammatory activity of the released drug was maintained.
Original language | English (US) |
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Pages (from-to) | 13757-13760 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 50 |
Issue number | 89 |
DOIs | |
State | Published - Oct 14 2014 |
Externally published | Yes |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry