Ethanol, the choline requirement, methylation and liver injury

Anthony J. Barak, Dean J. Tuma, Harriet C. Beckenhauer

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


The findings obtained in this laboratory and others over the past decade are discussed in order to formulate a thesis, indicating the adverse action of ethanol on a vital methylation process in the liver. Evidence is shown that the rat may have a means of compensating for this impairment in methylation whereas humans do not have this same ability to protect against this action of ethanol. These considerations may offer a basis of why rats are apparently more resistant to alcoholic liver injury than humans.

Original languageEnglish (US)
Pages (from-to)789-791
Number of pages3
JournalLife Sciences
Issue number9
StatePublished - Sep 2 1985

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)


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