Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene

Keyphrases

• Mouse Skin 100%
• SENCAR Mice 100%
• Abasic Site 100%
• Error-prone Repair 100%
• H-Ras Gene 100%
• DNA Depurination 100%
• 4-OHE2 66%
• Estradiol 66%
• HEC-RAS 66%
• Depurination 66%
• Carcinogen 33%
• Quinones 33%
• PCR Assay 33%
• Preneoplastic 33%
• Heteroduplex 33%
• DNA Glycosylase 33%
• Pyrene 33%
• Dibenzo 33%
• Error-prone 33%
• Repair Fidelity 33%
• KRAS mutation 33%
• Specific mutation 33%
• Mutation Spectrum 33%
• Threshold Level 33%
• Excision Repair 33%
• Active Repair 33%
• Disrepair 33%
• Genotoxic Compounds 33%
• Infidelity 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Sensitive to Carcinogenesis Mouse 100%
• 4 Hydroxyestradiol 66%
• Carcinogen 33%
• Quinone Derivative 33%
• Diethylstilbestrol 33%
• dibenzo[a,l]pyrene 33%
• DNA Glycosyltransferase 33%
• Heteroduplex 33%