Expanding the organismal scope of proteomics: Cross-species protein identification by mass spectrometry and its implications

Adam J. Liska; Andrej Shevchenko

doi:10.1002/pmic.200390004

Expanding the organismal scope of proteomics: Cross-species protein identification by mass spectrometry and its implications

Adam J. Liska, Andrej Shevchenko

Research output: Contribution to journal › Review article › peer-review

167 Scopus citations

Abstract

Due to the limited applicability of conventional protein identification methods to the proteomes of organisms with unsequenced genomes, researchers have developed approaches to identify proteins using mass spectrometry and sequence similarity database searches. Both the integration of mass spectrometry with bioinformatics and genomic sequencing drive the expanding organismal scope of proteomics.

Original language	English (US)
Pages (from-to)	19-28
Number of pages	10
Journal	Proteomics
Volume	3
Issue number	1
DOIs	https://doi.org/10.1002/pmic.200390004
State	Published - Jan 1 2003
Externally published	Yes

Keywords

Functional genomics
Genomics
Mass spectrometry
Phylogenetics
Protein complexes
Review

ASJC Scopus subject areas

Biochemistry
Molecular Biology

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10.1002/pmic.200390004

Cite this

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abstract = "Due to the limited applicability of conventional protein identification methods to the proteomes of organisms with unsequenced genomes, researchers have developed approaches to identify proteins using mass spectrometry and sequence similarity database searches. Both the integration of mass spectrometry with bioinformatics and genomic sequencing drive the expanding organismal scope of proteomics.",

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KW - Phylogenetics

KW - Protein complexes

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Expanding the organismal scope of proteomics: Cross-species protein identification by mass spectrometry and its implications

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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