Extra copies of chromosomes 7, 8, 12, 19, and 21 are recurrent in Adamantinoma

M. Kanamori, C. R. Antonescu, M. Scott, Jr Bridge R.S., J. R. Neff, S. S. Spanier, M. T. Scarborough, G. Vergara, H. G. Rosenthal, J. A. Bridge

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Adamantinoma of long bones is a rare neoplasm predominantly involving the tibia. Cytogenetic studies of adamantinoma are few. Cytogenetic or molecular cytogenetic analysis of four adamantinomas, and a review of eleven cases in the literature reveals extra copies of chromosomes 7, 8, 12, 19, and 21 as recurrent in this neoplasm. Adamantinoma may be confused with a variety of primary and metastatic epithelial and mesenchymal neoplasms. Observation of these aneuploidies may be useful in establishing the diagnosis of adamantinoma.

Original languageEnglish (US)
Pages (from-to)16-21
Number of pages6
JournalJournal of Molecular Diagnostics
Volume3
Issue number1
DOIs
StatePublished - 2001

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Molecular Medicine

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