Fabrication of assembled virus nanostructures on templates of chemoselective linkers formed by scanning probe nanolithography

Chin Li Cheung; Julio A. Camarero; Bruce W. Woods; Tianwei Lin; John E. Johnson; Jim J. De Yoreo

doi:10.1021/ja034479h

Fabrication of assembled virus nanostructures on templates of chemoselective linkers formed by scanning probe nanolithography

Chin Li Cheung, Julio A. Camarero, Bruce W. Woods, Tianwei Lin, John E. Johnson, Jim J. De Yoreo

Chemistry

Research output: Contribution to journal › Article

151 Scopus citations

Abstract

We have developed a multistep route to the fabrication of virus assembled nanostructures with chemoselective protein-to-surface linkers synthesized by an efficient solid-phase method. These linkers were used to create patterns of 30-to-50-nm-width-lines by scanning probe nanolithography. Genetically modified cow pea mosaic virus with unique cysteine residues at specific locations on their capsomers were assembled through covalent linkage on these patterns. The morphology of the assembled structures on these line patterns characterized by atomic force microscopy was found to be strongly influenced by the intervirion interactions.

Original language	English (US)
Pages (from-to)	6848-6849
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	125
Issue number	23
DOIs	https://doi.org/10.1021/ja034479h
State	Published - Jun 11 2003

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja034479h

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Cheung, C. L., Camarero, J. A., Woods, B. W., Lin, T., Johnson, J. E., & De Yoreo, J. J. (2003). Fabrication of assembled virus nanostructures on templates of chemoselective linkers formed by scanning probe nanolithography. Journal of the American Chemical Society, 125(23), 6848-6849. https://doi.org/10.1021/ja034479h

Fabrication of assembled virus nanostructures on templates of chemoselective linkers formed by scanning probe nanolithography. / Cheung, Chin Li; Camarero, Julio A.; Woods, Bruce W.; Lin, Tianwei; Johnson, John E.; De Yoreo, Jim J.

In: Journal of the American Chemical Society, Vol. 125, No. 23, 11.06.2003, p. 6848-6849.

Research output: Contribution to journal › Article

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