Face selective reduction of the exocyclic double bond in isatin derived spirocyclic lactones

Sandeep Rana, Amarnath Natarajan

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

We report an unusual face selective reduction of the exocyclic double bond in the α-methylene-γ-butyrolactone motif of spiro-oxindole systems. The spiro-oxindoles were assembled by an indium metal mediated Barbier-type reaction followed by an acid catalyzed lactonization.

Original languageEnglish (US)
Pages (from-to)244-247
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume11
Issue number2
DOIs
StatePublished - Jan 14 2013

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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