Facile assembly of large area cell arrays using patterned elastomeric surfaces

Karla Perez-Toralla, Angel Olivera-Torres, Mark Rose, Ruiguo Yang, Stephen Morin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

New tools for the rational design of reconfigurable cell arrays that are simple, scalable and easily implemented in tissue engineering and mechanosensing studies are reported here. A surface molding process that relies on the assembly of picoliter droplets into ordered arrays has been developed using micropatterned stretchable substrates. Aerosol microdroplets with cell cargo and uniform size distribution were generated and delivered using a novel microfluidic-based spray nozzle. Efficient cell assembly and proliferation was obtained inside the patterned areas.

Original languageEnglish (US)
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PublisherChemical and Biological Microsystems Society
Pages134-135
Number of pages2
ISBN (Electronic)9781733419000
StatePublished - 2019
Event23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland
Duration: Oct 27 2019Oct 31 2019

Publication series

Name23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
CountrySwitzerland
CityBasel
Period10/27/1910/31/19

Keywords

  • Aerosol Microfluidics
  • Cell Arrays
  • Chemical Patterning
  • Mechanosensing

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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