Factors affecting radioactive microsphere measurement of blood flow in pregnant guinea pigs.

S. Myers, J. W. Sparks, E. L. Makowski

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Comparative blood flow studies were performed in pregnant guinea pigs using radioactive microspheres to test the effects of different sphere sizes on blood flow measurements and the relationship between flows obtained intraoperatively and those performed after 5 days of recovery from anesthesia and surgery. We observed that 1.5% of the cardiac output was shunted through the microcirculation of the carcass, gut, skin and endomyometrium when 15 mu microspheres were used. Intraoperative measurements of heart rate, cardiac output and placental blood flow are significantly lower than measurements made after 5 days recovery. These reductions were ameliorated with the addition of a continuous infusion of isoproterenol and the deletion of atropine from the anesthetic.

Original languageEnglish (US)
Pages (from-to)522-526
Number of pages5
JournalLaboratory animal science
Volume36
Issue number5
StatePublished - Oct 1986

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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