TY - JOUR
T1 - Factors associated with receipt of hematopoietic cell transplantation for acute lymphoblastic leukemia
AU - Manikkam Umakanthan, Jayadev
AU - Chen, Baojiang
AU - Gundabolu, Krishna
AU - Bhatt, Vijaya R.
N1 - Funding Information:
This work was supported in part by 2016-2017 Physician-Scientist Training Program Grant from the College of Medicine, University of Nebraska Medical Center (V Bhatt). The National Cancer Database (NCDB) is a joint project of the Commission on Cancer (CoC) of the American College of Surgeons and the American Cancer Society. The CoC's NCDB and the hospitals participating in the CoC NCDB are the source of the de-identified data used herein; they have not verified and are not responsible for the statistical validity of the data analysis or the conclusions derived by the authors.
Funding Information:
This work was supported in part by 2016–2017 Physician–Scientist Training Program Grant from the College of Medicine, University of Nebraska Medical Center (V Bhatt). The National Cancer Database (NCDB) is a joint project of the Commission on Cancer (CoC) of the American College of Surgeons and the American Cancer Society. The CoC’s NCDB and the hospitals participating in the CoC NCDB are the source of the de-identified data used herein; they have not verified and are not responsible for the statistical validity of the data analysis or the conclusions derived by the authors.
Publisher Copyright:
© 2018 Future Medicine Ltd.
PY - 2018/6
Y1 - 2018/6
N2 - Aim: To evaluate practice patterns of hematopoietic cell transplantation (HCT) for acute lymphoblastic leukemia. Materials & methods: We utilized the National Cancer Database to extract patient-level data of adults (aged 18-80 years) diagnosed with acute lymbhoblastic leukemia between 2003 and 2012. We performed multivariable logistic regression to determine variables associated with the use of HCT. Results: Out of a total of 11,871 patients, 12.7% received HCT. In a multivariate analysis, older age, male sex, higher Charlson co-morbidity score, nonacademic treatment center, poor education and Medicare/Medicaid or no insurance were associated with lower likelihood of receiving HCT. Conclusion: Our study demonstrates variations in the utilization of HCT based on socioeconomic and health system factors.
AB - Aim: To evaluate practice patterns of hematopoietic cell transplantation (HCT) for acute lymphoblastic leukemia. Materials & methods: We utilized the National Cancer Database to extract patient-level data of adults (aged 18-80 years) diagnosed with acute lymbhoblastic leukemia between 2003 and 2012. We performed multivariable logistic regression to determine variables associated with the use of HCT. Results: Out of a total of 11,871 patients, 12.7% received HCT. In a multivariate analysis, older age, male sex, higher Charlson co-morbidity score, nonacademic treatment center, poor education and Medicare/Medicaid or no insurance were associated with lower likelihood of receiving HCT. Conclusion: Our study demonstrates variations in the utilization of HCT based on socioeconomic and health system factors.
KW - acute lymphoblastic leukemia
KW - healthcare disparities
KW - hematopoietic cell transplant
KW - transplant utilization
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U2 - 10.2217/fon-2017-0599
DO - 10.2217/fon-2017-0599
M3 - Article
C2 - 29712491
AN - SCOPUS:85048048721
SN - 1479-6694
VL - 14
SP - 1253
EP - 1260
JO - Future Oncology
JF - Future Oncology
IS - 13
ER -