Failure of elimination of paternal mitochondrial DNA in abnormal embryos

Justin St John, Denny Sakkas, Konstantina Dimitriadi, Annette Barnes, Victoria Maclin, Jacques Ramey, Christopher Barratt, Christopher De Jonge

Research output: Contribution to journalArticle

71 Scopus citations

Abstract

Paternal mitochondrial DNA is normally eliminated from mammalian embryos. We have shown the presence of paternal mtDNA at the blastocyst stage in some abnormal human embryos.

Original languageEnglish (US)
Pages (from-to)200
Number of pages1
JournalLancet
Volume355
Issue number9199
DOIs
StatePublished - Jan 15 2000

ASJC Scopus subject areas

  • Medicine(all)

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    St John, J., Sakkas, D., Dimitriadi, K., Barnes, A., Maclin, V., Ramey, J., Barratt, C., & De Jonge, C. (2000). Failure of elimination of paternal mitochondrial DNA in abnormal embryos. Lancet, 355(9199), 200. https://doi.org/10.1016/S0140-6736(99)03842-8